Language: JP/EN

ABOUT US

 We have been focusing on "Transporters", membrane proteins responsible for the selective transport of solutes across the biological membranes. By understanding of the structure and function of transporters, and by elucidating the intermolecular interactions and the regulatory mechanisms of transport functions, we would like to reveal the importance of transporters in various cell- and tissue-specific functions under physiological and pathological conditions. Evaluation of transporters as novel targets for drug developments is also in our scope. To achieve that, in addition to traditional biochemical and pharmacological transport analyses, we apply a wide range of experimental techniques such as proteomic analysis specialized for membrane proteins, phosphorylated proteomics, metabolomics, phenotypical analysis of genetically modified animals. Our research covers the multiple biological hierarchy including molecules, cells, tissues, organs and whole body.

NEWS & TOPICS

  • Prof. Kanai gave his final lecture. Thank you very much for your participation! (2024.03.25)
  • Mr. Nishikubo was selected as the High achievers of PhD course AY2023 ! (2024.03.25)
  • Mr. Zhou won the prize of "Excellent Presentation Award" at the 144th Kinki Branch Meeting of the Japanese Pharmacological Society! (20242.03.20)
  • Mr. Ma's paperwas published in J Pharmacol Sci. (2024.03.13)
  • Ms. Chen's paper was published in Sci Rep. (2024.02.26)
  • Mr. Liu's paper was published in J Pharmacol Sci. (2024.02.24)
  • Mr. Zhou's paper was published in J Pharmacol Sci. (2024.01.30)
  • Mr. Nishikubo won the prize of "Excellent Student Presentation Award" at the 97nd Anjual Meeting of the Japanese Pharmacological Society! (2023.12.16)
  • Ms. Shi's paper was published in Sci Rep. (2023.08.25)
  • Mr. Nishikubo's paper was published in Cancer Cell Int. (2023.06.15)
  • A collaborative paper on the relationship between intestinal tumor initiation and LAT1 was published in J Gastroenterol. (2023.02.05)
  • Dr. Miyabe's paper won The JPS Prize 2022 Awards !(2023.01.23)
  • Assistant Prof. Okanishi's paper was published in Cancer Metab. (2022.11.10)
  • Mr. Nishikubo's paper was published in J Cell Mol Med. (2022.09.07)
  • A collaborative paper on the Cryo-EM structure of EAAT2 and the mechanims of action of its selective inhibitor was published in Nat Commun. (2022.08.09)
  • Mr. Nishikubo won the prize of "Excellent Presentation Award" at the 141st Kinki Branch Meeting of the Japanese Pharmacological Society! (2022.07.01)
  • Ms. Ohtsu's paper was published in J Pharmacol Sci. (2022.06.13)
  • Prof. Kanai's review paper was published in Pharmacol Ther. (2021.08.11)
  • Dr. Xu became Assistant Prof. (2021.04.01)
  • Assistant Prof. Okuda has moved as Associate Prof. at the Food Biotechnol and Struct Biol Lab, Dept of Appl Biol Chem, Grad Sch of Agric Life Sci, The Univ of Tokyo. (2021.04.01)
  • Dr. Jin was selected as the High achievers of PhD course AY2020 ! (2021.03.24)
  • Assistant Prof. Ohagaki became Associate Prof. (2021.03.01)
  • Assistant Prof. Okanishi's paper was published in Cancer Sci. (2020.12.02)
  • Ms. Quan and Assistant Prof. Ohgaki's paper was published in J Exp Clin Cancer Res. (2020.11.30)
  • Prof. Kanai was selected as the recipient of "Highly Cited Researchers 2020" in the field of "Pharmacology and Toxicology" by Clarivate Analytics! (2020.11.20)
  • A collaborative paper on a novel mutation prostaglandin transporter SLCO2A1 related to chronic enteropathy was published in PLoS One. (2020.11.09)
  • A collaborative paper on the ligand-induced stabilization of Ser/Thr protein kinase was published in FEBS Lett. (2020.11.07)
  • Ms. Jin's paper was published in J Pharmacol Exp Ther. (2020.09.27)
  • Mr. Nishikubo won the prize of "Young Investigator Award" at the 137th Kinki Branch Meeting of the Japanese Pharmacological Society! (2020.07.07)
  • Prof. Kanai won the prize of The 3rd Japan Medical Research and Development Grand Prize, the Prime Minister's Prize! (2020.01.10)
  • Mr. Liu won the prize of "Young Investigator Award" at the 136th Kinki Branch Meeting of the Japanese Pharmacological Society! (2019.11.23)
  • A collaborative paper on the Cryo-EM structure of LAT1-4F2hc complex was published in Nat Struct Mol Biol. (2019.06.3)
  • Dr. Miyabe won the prize of "Young Investigator Award" at the 92nd Annual Meeting of the Japanese Pharmacological Society! (2019.03.16)
  • The 92nd Annual Meeting of the Japanese Pharmacological Society was held in Osaka.
    Prof. Kanai has served as the president of the meeting. (2019.03.14-16)
  • Dr. Miyabe's paper was published in J Pharmacol Sci. (2018.02.18)
  • A review article on amino acid transporters by Prof. Kanai and Prof. M. Hediger was published in TIBS. (2018.08.31)
  • Prof. X. He from Tianjin University of Traditional Chinese Medicine has visited our lab by JSPS International Fellowships for Research in Japan. (2018.07.21-09.24)
  • Prof. Kanai was selected as the Second Vice President of IUPHAR (International Union of Basic and Clinical Pharmacology). (2018.07.04)
  • Ms. Jin and Mr. Huang won the prize of "Excellent Poster Presentation" at the Campus Asia Faculty meeting, Symopsium and Workshop! (2018.03.07)
  • We have renewed our website! (2018.03.01)
  • Assistant Prof. Ohgaki's paper was published in Sci Rep. (2017.12.13)
  • The 132nd Japanese Pharmacological Society Kinki Bransh Meeting was held in Osaka.
    Prof. Kanai has served as the chairman of the meeting. (2017.11.24)
  • Associate Prof. Nagamori has moved as a professor at the Laboratory of Bio-Molecular Dynamics, Department of Collaborative Research, Nara Medical University. (2017.10.01)
  • Assistant Prof. Ohgaki's paper was published in Mol Cell Biol. (2017.06.01)
  • A news article on our research was released by a newspaper, Yomiuri Shimbun. (2017.03.15)
  • Dr. Kongpracha's paper was published in J Pharmacol Sci. (2017.02.09)
    • (From 2017.1.1)